Physician Resources
Since pioneering RELIEF®, Vitruvia has partnered with the world’s leading medical, biomechanical and performance experts.
DR. Thomas Best M.D., Ph.D., Team Physician for University of Miami Hurricanes and Miami Marlins
MD, Former Director of University of Pennsylvania Spine and Rehabilitation Center

1: Yang J, Chen Z, Pan D, Li H, Shen J. Umbilical Cord-Derived Mesenchymal Stem Cell-Derived Exosomes Combined Pluronic F127 Hydrogel Promote Chronic Diabetic Wound Healing and Complete Skin Regeneration. Int J Nanomedicine. 2020 Aug 11;15:5911-5926. doi: 10.2147/IJN.S249129. PMID: 32848396; PMCID: PMC7429232.

2: Zhu Y, Wang Y, Jia Y, Xu J, Chai Y. Roxadustat promotes angiogenesis through HIF-1α/VEGF/VEGFR2 signaling and accelerates cutaneous wound healing in diabetic rats. Wound Repair Regen. 2019 Jul;27(4):324-334. doi: 10.1111/wrr.12708. Epub 2019 Feb 28. PMID: 30817065.

3: Huang X, Liang P, Jiang B, Zhang P, Yu W, Duan M, Guo L, Cui X, Huang M, Huang X. Hyperbaric oxygen potentiates diabetic wound healing by promoting fibroblast cell proliferation and endothelial cell angiogenesis. Life Sci. 2020 Oct 15;259:118246. doi: 10.1016/j.lfs.2020.118246. Epub 2020 Aug 10. PMID: 32791151.

4: Bullard JD, Lei J, Lim JJ, Massee M, Fallon AM, Koob TJ. Evaluation of dehydrated human umbilical cord biological properties for wound care and soft tissue healing. J Biomed Mater Res B Appl Biomater. 2019 May;107(4):1035-1046. doi: 10.1002/jbm.b.34196. Epub 2018 Sep 10. PMID: 30199609; PMCID: PMC6585686.

5: Hsieh L, Nugent D. Factor XIII deficiency. Haemophilia. 2008 Nov;14(6):1190-200. doi: 10.1111/j.1365-2516.2008.01857.x. PMID: 19141159.

6: Gaebel R, Furlani D, Sorg H, Polchow B, Frank J, Bieback K, Wang W, Klopsch C, Ong LL, Li W, Ma N, Steinhoff G. Cell origin of human mesenchymal stem cells determines a different healing performance in cardiac regeneration. PLoS One. 2011 Feb 10;6(2):e15652. doi: 10.1371/journal.pone.0015652. PMID: 21347366; PMCID: PMC3037376.

7: Yan ZJ, Wang D, Ye Z, Fan T, Wu G, Deng L, Yang L, Li B, Liu J, Ma T, Dong C, Li ZT, Xiao L, Wang Y, Wang W, Hou JL. Artificial Aquaporin That Restores Wound Healing of Impaired Cells. J Am Chem Soc. 2020 Sep 16;142(37):15638-15643. doi: 10.1021/jacs.0c00601. Epub 2020 Sep 3. PMID: 32876439.

8: Mouritzen MV, Andrea A, Qvist K, Poulsen SS, Jenssen H. Immunomodulatory potential of Nisin A with application in wound healing. Wound Repair Regen. 2019 Nov;27(6):650-660. doi: 10.1111/wrr.12743. Epub 2019 Jul 9. PMID: 31287619.

9: Wang TY, Wang W, Li FF, Chen YC, Jiang D, Chen YD, Yang H, Liu L, Lu M, Sun JS, Gu DM, Wang J, Wang AP. Maggot excretions/secretions promote diabetic wound angiogenesis via miR18a/19a - TSP-1 axis. Diabetes Res Clin Pract. 2020 Jul;165:108140. doi: 10.1016/j.diabres.2020.108140. Epub 2020 Apr 8. PMID: 32277954.

10: Feng Y, Zhan F, Zhong Y, Tan B. Effects of human umbilical cord mesenchymal stem cells derived from exosomes on migration ability of endometrial glandular epithelial cells. Mol Med Rep. 2020 Aug;22(2):715-722. doi: 10.3892/mmr.2020.11137. Epub 2020 May 7. PMID: 32626977; PMCID: PMC7339775.

11: Qi WY, Gao XM, Ma ZY, Xia CL, Xu HM. Antiangiogenic activity of terpenoids from Euphorbia neriifolia Linn. Bioorg Chem. 2020 Mar;96:103536. doi: 10.1016/j.bioorg.2019.103536. Epub 2019 Dec 28. PMID: 31972463.

12: Ma J, Zhao Y, Sun L, Sun X, Zhao X, Sun X, Qian H, Xu W, Zhu W. Exosomes Derived from Akt-Modified Human Umbilical Cord Mesenchymal Stem Cells Improve Cardiac Regeneration and Promote Angiogenesis via Activating Platelet-Derived Growth Factor D. Stem Cells Transl Med. 2017 Jan;6(1):51-59. doi: 10.5966/sctm.2016-0038. Epub 2016 Sep 22. PMID: 28170176; PMCID: PMC5442756.

13: Zhao Y, Wang X, Yang S, Song X, Sun N, Chen C, Zhang Y, Yao D, Huang J, Wang J, Zhang Y, Yang B. Kanglexin accelerates diabetic wound healing by promoting angiogenesis via FGFR1/ERK signaling. Biomed Pharmacother. 2020 Dec;132:110933. doi: 10.1016/j.biopha.2020.110933. Epub 2020 Oct 28. PMID: 33128943.

14: Rahman HS, Tan BL, Othman HH, Chartrand MS, Pathak Y, Mohan S, Abdullah R, Alitheen NB. An Overview of In Vitro, In Vivo, and Computational Techniques for Cancer-Associated Angiogenesis Studies. Biomed Res Int. 2020 Dec 10;2020:8857428. doi: 10.1155/2020/8857428. PMID: 33381591; PMCID: PMC7748901.

15: Liu X, Yang Y, Guo X, Liu L, Wu K, Yu M. The Antiangiogenesis Effect of Pirfenidone in Wound Healing In Vitro. J Ocul Pharmacol Ther. 2017 Nov;33(9):693-703. doi: 10.1089/jop.2017.0007. Epub 2017 Sep 21. PMID: 28933986.

16: Jia W, Hu H, Li A, Deng H, Hogue CL, Mauro JC, Zhang C, Fu Q. Glass- activated regeneration of volumetric muscle loss. Acta Biomater. 2020 Feb;103:306-317. doi: 10.1016/j.actbio.2019.12.007. Epub 2019 Dec 9. PMID: 31830584.

17: Zhang Y, Pan Y, Liu Y, Li X, Tang L, Duan M, Li J, Zhang G. Exosomes derived from human umbilical cord blood mesenchymal stem cells stimulate regenerative wound healing via transforming growth factor-β receptor inhibition. Stem Cell Res Ther. 2021 Aug 3;12(1):434. doi: 10.1186/s13287-021-02517-0. PMID: 34344478; PMCID: PMC8336384.

18: Gabrielyan A, Quade M, Gelinsky M, Rösen-Wolff A. IL-11 and soluble VCAM-1 are important components of Hypoxia Conditioned Media and crucial for Mesenchymal Stromal Cells attraction. Stem Cell Res. 2020 May;45:101814. doi: 10.1016/j.scr.2020.101814. Epub 2020 Apr 20. PMID: 32334367.

19: Dai F, Gao L, Zhao Y, Wang C, Xie S. Farrerol inhibited angiogenesis through Akt/mTOR, Erk and Jak2/Stat3 signal pathway. Phytomedicine. 2016 Jun 15;23(7):686-93. doi: 10.1016/j.phymed.2016.03.008. Epub 2016 Apr 9. PMID: 27235707.

20: Chen Z, Haus JM, Chen L, Wu SC, Urao N, Koh TJ, Minshall RD. CCL28-induced CCR10/eNOS interaction in angiogenesis and skin wound healing. FASEB J. 2020 Apr;34(4):5838-5850. doi: 10.1096/fj.201902060R. Epub 2020 Mar 2. PMID: 32124475; PMCID: PMC7136142.

21: Jian J, Zheng Z, Zhang K, Rackohn TM, Hsu C, Levin A, Enjamuri DR, Zhang X, Ting K, Soo C. Fibromodulin promoted in vitro and in vivo angiogenesis. Biochem Biophys Res Commun. 2013 Jul 5;436(3):530-535. doi: 10.1016/j.bbrc.2013.06.005. Epub 2013 Jun 11. PMID: 23770359; PMCID: PMC4007216.

22: Berrich M, Kieda C, Grillon C, Monteil M, Lamerant N, Gavard J, Boulouis HJ, Haddad N. Differential effects of Bartonella henselae on human and feline macro- and micro-vascular endothelial cells. PLoS One. 2011;6(5):e20204. doi: 10.1371/journal.pone.0020204. Epub 2011 May 27. PMID: 21637717; PMCID: PMC3103534.

23: Kim DW, Jo YY, Garagiola U, Choi JY, Kang YJ, Oh JH, Kim SG. Increased Level of Vascular Endothelial Growth Factors by 4-hexylresorcinol is Mediated by Transforming Growth Factor-β1 and Accelerates Capillary Regeneration in the Burns in Diabetic Animals. Int J Mol Sci. 2020 May 14;21(10):3473. doi: 10.3390/ijms21103473. PMID: 32423083; PMCID: PMC7279008.

24: Pan L, Tang J, Liu H, Cheng B. Sympathetic nerves: How do they affect angiogenesis, particularly during wound healing of soft tissues? Clin Hemorheol Microcirc. 2016;62(2):181-91. doi: 10.3233/CH-152019. PMID: 26484721.

25: Li H, He J, Yu H, Green CR, Chang J. Bioglass promotes wound healing by affecting gap junction connexin 43 mediated endothelial cell behavior. Biomaterials. 2016 Apr;84:64-75. doi: 10.1016/j.biomaterials.2016.01.033. Epub 2016 Jan 19. PMID: 26821121.

26: Abate M, Pisanti S, Caputo M, Citro M, Vecchione C, Martinelli R. 3-Hydroxytyrosol Promotes Angiogenesis In Vitro by Stimulating Endothelial Cell Migration. Int J Mol Sci. 2020 May 22;21(10):3657. doi: 10.3390/ijms21103657. PMID: 32455901; PMCID: PMC7279499.

27: Boucher JM, Clark RP, Chong DC, Citrin KM, Wylie LA, Bautch VL. Dynamic alterations in decoy VEGF receptor-1 stability regulate angiogenesis. Nat Commun. 2017 Jun 7;8:15699. doi: 10.1038/ncomms15699. PMID: 28589930; PMCID: PMC5467243.

28: Zhong C, Li P, Argade S, Liu L, Chilla' A, Liang W, Xin H, Eliceiri B, Choudhury B, Ferrara N. Inhibition of protein glycosylation is a novel pro- angiogenic strategy that acts via activation of stress pathways. Nat Commun. 2020 Dec 10;11(1):6330. doi: 10.1038/s41467-020-20108-0. PMID: 33303737; PMCID: PMC7730427.

29: Yu Y, Chen R, Sun Y, Pan Y, Tang W, Zhang S, Cao L, Yuan Y, Wang J, Liu C. Manipulation of VEGF-induced angiogenesis by 2-N, 6-O-sulfated chitosan. Acta Biomater. 2018 Apr 15;71:510-521. doi: 10.1016/j.actbio.2018.02.031. Epub 2018 Mar 12. PMID: 29501817.

30: Cunha F, Rajnicek AM, McCaig CD. Electrical Stimulation Directs Migration, Enhances and Orients Cell Division and Upregulates the Chemokine Receptors CXCR4 and CXCR2 in Endothelial Cells. J Vasc Res. 2019;56(1):39-53. doi: 10.1159/000495311. Epub 2019 Apr 17. PMID: 30995642.

31: Stilley JA, Guan R, Duffy DM, Segaloff DL. Signaling through FSH receptors on human umbilical vein endothelial cells promotes angiogenesis. J Clin Endocrinol Metab. 2014 May;99(5):E813-20. doi: 10.1210/jc.2013-3186. Epub 2014 Feb 14. PMID: 24527712; PMCID: PMC4010687.

32: Zheng L, Amano K, Iohara K, Ito M, Imabayashi K, Into T, Matsushita K, Nakamura H, Nakashima M. Matrix metalloproteinase-3 accelerates wound healing following dental pulp injury. Am J Pathol. 2009 Nov;175(5):1905-14. doi: 10.2353/ajpath.2009.080705. Epub 2009 Oct 15. PMID: 19834065; PMCID: PMC2774055.

33: Santini MP, Malide D, Hoffman G, Pandey G, D'Escamard V, Nomura-Kitabayashi A, Rovira I, Kataoka H, Ochando J, Harvey RP, Finkel T, Kovacic JC. Tissue- Resident PDGFRα+ Progenitor Cells Contribute to Fibrosis versus Healing in a Context- and Spatiotemporally Dependent Manner. Cell Rep. 2020 Jan 14;30(2):555-570.e7. doi: 10.1016/j.celrep.2019.12.045. PMID: 31940496; PMCID: PMC7030884.

34: Yang R, Wang J, Zhou Z, Qi S, Ruan S, Lin Z, Xin Q, Lin Y, Chen X, Xie J. Curcumin promotes burn wound healing in mice by upregulating caveolin-1 in epidermal stem cells. Phytother Res. 2019 Feb;33(2):422-430. doi: 10.1002/ptr.6238. Epub 2018 Nov 20. PMID: 30461085.

35: Feng X, Zhang X, Li S, Zheng Y, Shi X, Li F, Guo S, Yang J. Preparation of aminated fish scale collagen and oxidized sodium alginate hybrid hydrogel for enhanced full-thickness wound healing. Int J Biol Macromol. 2020 Dec 1;164:626-637. doi: 10.1016/j.ijbiomac.2020.07.058. Epub 2020 Jul 12. PMID: 32668308.

36: Zhang Q, Zhou M, Wu X, Li Z, Liu B, Gao W, Yue J, Liu T. Promoting therapeutic angiogenesis of focal cerebral ischemia using thrombospondin-4 (TSP4) gene-modified bone marrow stromal cells (BMSCs) in a rat model. J Transl Med. 2019 Apr 4;17(1):111. doi: 10.1186/s12967-019-1845-z. PMID: 30947736; PMCID: PMC6449913.

37: Radmanesh F, Abandansari HS, Pahlavan S, Alikhani M, Karimi M, Rajabi S, Kazemi B, Baharvand H. Optimization of miRNA delivery by using a polymeric conjugate based on deoxycholic acid-modified polyethylenimine. Int J Pharm. 2019 Jun 30;565:391-408. doi: 10.1016/j.ijpharm.2019.05.009. Epub 2019 May 11. PMID: 31085260.

38: Reine TM, Vuong TT, Rutkovskiy A, Meen AJ, Vaage J, Jenssen TG, Kolset SO. Serglycin in Quiescent and Proliferating Primary Endothelial Cells. PLoS One. 2015 Dec 22;10(12):e0145584. doi: 10.1371/journal.pone.0145584. PMID: 26694746; PMCID: PMC4687888.

39: Xu M, Hua Y, Qi Y, Meng G, Yang S. Exogenous hydrogen sulphide supplement accelerates skin wound healing via oxidative stress inhibition and vascular endothelial growth factor enhancement. Exp Dermatol. 2019 Jul;28(7):776-785. doi: 10.1111/exd.13930. Epub 2019 May 15. PMID: 30927279.

40: Wu ZB, Cai L, Lin SJ, Leng ZG, Guo YH, Yang WL, Chu YW, Yang SH, Zhao WG. Heat Shock Protein 47 Promotes Glioma Angiogenesis. Brain Pathol. 2016 Jan;26(1):31-42. doi: 10.1111/bpa.12256. Epub 2015 May 7. PMID: 25758142.

41: Jiang S, Li Y, Lin T, Yuan L, Li Y, Wu S, Xia L, Shen H, Lu J. IL-35 Inhibits Angiogenesis through VEGF/Ang2/Tie2 Pathway in Rheumatoid Arthritis. Cell Physiol Biochem. 2016;40(5):1105-1116. doi: 10.1159/000453165. Epub 2016 Dec 14. PMID: 27960151.

42: Sáez T, de Vos P, Kuipers J, Sobrevia L, Faas MM. Fetoplacental endothelial exosomes modulate high d-glucose-induced endothelial dysfunction. Placenta. 2018 Jun;66:26-35. doi: 10.1016/j.placenta.2018.04.010. Epub 2018 Apr 21. PMID: 29884299.

43: Hu Q, Guo Y, Zhang T, Feng J, Wang J, Dong X, Chen Y, Nie R, Feng Z, Huang Y, Deng M, Ke X. Importance of β2AR elevation for re- endothelialization capacity mediated by late endothelial progenitor cells in hypertensive patients. Am J Physiol Heart Circ Physiol. 2021 Feb 1;320(2):H867-H880. doi: 10.1152/ajpheart.00596.2020. Epub 2020 Dec 24. PMID: 33356961.

44: Sun G, Li G, Li D, Huang W, Zhang R, Zhang H, Duan Y, Wang B. hucMSC derived exosomes promote functional recovery in spinal cord injury mice via attenuating inflammation. Mater Sci Eng C Mater Biol Appl. 2018 Aug 1;89:194-204. doi: 10.1016/j.msec.2018.04.006. Epub 2018 Apr 10. PMID: 29752089.

45: Zhou X, Patel D, Sen S, Shanmugam V, Sidawy A, Mishra L, Nguyen BN. Poly- ADP-ribose polymerase inhibition enhances ischemic and diabetic wound healing by promoting angiogenesis. J Vasc Surg. 2017 Apr;65(4):1161-1169. doi: 10.1016/j.jvs.2016.03.407. Epub 2016 Jun 8. PMID: 27288104.

46: Tzoneva R, Uzunova V, Apostolova S, Krüger-Genge A, Neffe AT, Jung F, Lendlein A. Angiogenic potential of endothelial and tumor cells seeded on gelatin-based hydrogels in response to electrical stimulations. Clin Hemorheol Microcirc. 2016;64(4):941-949. doi: 10.3233/CH-168040. PMID: 27792001.

47: He L, Tu HJ, He WF, Guo LL, Yu SX, Li J, Wu Q, Li J. Lentiviral-mediated overexpression of homeobox A4 by human umbilical cord mesenchymal stem cells repairs full-thickness skin defects. Mol Med Rep. 2015 May;11(5):3517-22. doi: 10.3892/mmr.2015.3208. Epub 2015 Jan 16. PMID: 25592724.

48: Tomioka H, Nakagami H, Tenma A, Saito Y, Kaga T, Kanamori T, Tamura N, Tomono K, Kaneda Y, Morishita R. Novel anti-microbial peptide SR-0379 accelerates wound healing via the PI3 kinase/Akt/mTOR pathway. PLoS One. 2014 Mar 27;9(3):e92597. doi: 10.1371/journal.pone.0092597. PMID: 24675668; PMCID: PMC3968008.

49: Maltaneri RE, Schiappacasse A, Chamorro ME, Nesse AB, Vittori DC. Aquaporin-1 plays a key role in erythropoietin-induced endothelial cell migration. Biochim Biophys Acta Mol Cell Res. 2020 Jan;1867(1):118569. doi: 10.1016/j.bbamcr.2019.118569. Epub 2019 Oct 30. PMID: 31676353.

50: Park JY, Shin MS, Hwang GS, Yamabe N, Yoo JE, Kang KS, Kim JC, Lee JG, Ham J, Lee HL. Beneficial Effects of Deoxyshikonin on Delayed Wound Healing in Diabetic Mice. Int J Mol Sci. 2018 Nov 20;19(11):3660. doi: 10.3390/ijms19113660. PMID: 30463303; PMCID: PMC6274849.

51: Guo J, Linetsky M, Yu AO, Zhang L, Howell SJ, Folkwein HJ, Wang H, Salomon RG. 4-Hydroxy-7-oxo-5-heptenoic Acid Lactone Induces Angiogenesis through Several Different Molecular Pathways. Chem Res Toxicol. 2016 Dec 19;29(12):2125-2135. doi: 10.1021/acs.chemrestox.6b00233. Epub 2016 Nov 11. PMID: 27806561; PMCID: PMC5349710.

52: Futakuchi A, Inoue T, Fujimoto T, Kuroda U, Inoue-Mochita M, Takahashi E, Ohira S, Tanihara H. Molecular Mechanisms Underlying the Filtration Bleb- Maintaining Effects of Suberoylanilide Hydroxamic Acid (SAHA). Invest Ophthalmol Vis Sci. 2017 Apr 1;58(4):2421-2429. doi: 10.1167/iovs.16-21403. PMID: 28448670.

53: Passaretti F, Tia M, D'Esposito V, De Pascale M, Del Corso M, Sepulveres R, Liguoro D, Valentino R, Beguinot F, Formisano P, Sammartino G. Growth-promoting action and growth factor release by different platelet derivatives. Platelets. 2014;25(4):252-6. doi: 10.3109/09537104.2013.809060. Epub 2013 Jul 15. PMID: 23855408.

54: Inglis S, Christensen D, Wilson DI, Kanczler JM, Oreffo RO. Human endothelial and foetal femur-derived stem cell co-cultures modulate osteogenesis and angiogenesis. Stem Cell Res Ther. 2016 Jan 18;7:13. doi: 10.1186/s13287-015-0270-3. PMID: 26781715; PMCID: PMC4717648.

55: Ferreira AK, Freitas VM, Levy D, Ruiz JL, Bydlowski SP, Rici RE, Filho OM, Chierice GO, Maria DA. Anti-angiogenic and anti-metastatic activity of synthetic phosphoethanolamine. PLoS One. 2013;8(3):e57937. doi: 10.1371/journal.pone.0057937. Epub 2013 Mar 14. PMID: 23516420; PMCID: PMC3597720.

56: Gärtner A, Pereira T, Alves MG, Armada-da-Silva PA, Amorim I, Gomes R, Ribeiro J, França ML, Lopes C, Carvalho RA, Socorro S, Oliveira PF, Porto B, Sousa R, Bombaci A, Ronchi G, Fregnan F, Varejão AS, Luís AL, Geuna S, Maurício AC. Use of poly(DL-lactide-ε-caprolactone) membranes and mesenchymal stem cells from the Wharton's jelly of the umbilical cord for promoting nerve regeneration in axonotmesis: in vitro and in vivo analysis. Differentiation. 2012 Dec;84(5):355-65. doi: 10.1016/j.diff.2012.10.001. Epub 2012 Nov 7. Erratum in: Differentiation. 2013 Feb;85(3):119. Alves, Marco G [added];Carvalho, Rui A [added];Socorro, S [added]; Oliveira, Pedro F [added]. PMID: 23142731.

57: Oh SY, Lee SJ, Jung YH, Lee HJ, Han HJ. Arachidonic acid promotes skin wound healing through induction of human MSC migration by MT3-MMP-mediated fibronectin degradation. Cell Death Dis. 2015 May 7;6(5):e1750. doi: 10.1038/cddis.2015.114. PMID: 25950480; PMCID: PMC4669694.

58: Teramatsu Y, Maeda H, Sugii H, Tomokiyo A, Hamano S, Wada N, Yuda A, Yamamoto N, Koori K, Akamine A. Expression and effects of epidermal growth factor on human periodontal ligament cells. Cell Tissue Res. 2014 Sep;357(3):633-43. doi: 10.1007/s00441-014-1877-x. Epub 2014 May 22. PMID: 24850273.

59: Huang L, Wong YP, Gu H, Cai YJ, Ho Y, Wang CC, Leung TY, Burd A. Stem cell- like properties of human umbilical cord lining epithelial cells and the potential for epidermal reconstitution. Cytotherapy. 2011 Feb;13(2):145-55. doi: 10.3109/14653249.2010.509578. Epub 2010 Aug 24. PMID: 20735166.

60: Ouyang Z, Tan T, Zhang X, Wan J, Zhou Y, Jiang G, Yang D, Liu T. LncRNA ENST00000563492 promoting the osteogenesis-angiogenesis coupling process in bone mesenchymal stem cells (BMSCs) by functions as a ceRNA for miR-205-5p. Cell Death Dis. 2020 Jun 25;11(6):486. doi: 10.1038/s41419-020-2689-4. PMID: 32587236; PMCID: PMC7316863.

61: Mun GI, Jang SI, Boo YC. Laminar shear stress induces the expression of aquaporin 1 in endothelial cells involved in wound healing. Biochem Biophys Res Commun. 2013 Jan 11;430(2):554-9. doi: 10.1016/j.bbrc.2012.11.114. Epub 2012 Dec 7. PMID: 23220481.

62: Zhang W, Shao C, Yu F, Chen J, Fu Y, Fan X. Y-27632 Promotes the Repair Effect of Umbilical Cord Blood-Derived Endothelial Progenitor Cells on Corneal Endothelial Wound Healing. Cornea. 2021 Feb 1;40(2):203-214. doi: 10.1097/ICO.0000000000002560. PMID: 33086282.

63: Niu G, Sun L, Pei Y, Wang D. Oleanolic Acid Inhibits Colorectal Cancer Angiogenesis by Blocking the VEGFR2 Signaling Pathway. Anticancer Agents Med Chem. 2018;18(4):583-590. doi: 10.2174/1871520617666171020124916. PMID: 29065844.

64: Novizio N, Belvedere R, Pessolano E, Tosco A, Porta A, Perretti M, Campiglia P, Filippelli A, Petrella A. Annexin A1 Released in Extracellular Vesicles by Pancreatic Cancer Cells Activates Components of the Tumor Microenvironment, through Interaction with the Formyl-Peptide Receptors. Cells. 2020 Dec 18;9(12):2719. doi: 10.3390/cells9122719. PMID: 33353163; PMCID: PMC7767312.

65: Vuong TT, Reine TM, Sudworth A, Jenssen TG, Kolset SO. Syndecan-4 is a major syndecan in primary human endothelial cells in vitro, modulated by inflammatory stimuli and involved in wound healing. J Histochem Cytochem. 2015 Apr;63(4):280-92. doi: 10.1369/0022155415568995. Epub 2015 Jan 9. PMID: 25575567; PMCID: PMC4374057.

66: Barcelos LS, Duplaa C, Kränkel N, Graiani G, Invernici G, Katare R, Siragusa M, Meloni M, Campesi I, Monica M, Simm A, Campagnolo P, Mangialardi G, Stevanato L, Alessandri G, Emanueli C, Madeddu P. Human CD133+ progenitor cells promote the healing of diabetic ischemic ulcers by paracrine stimulation of angiogenesis and activation of Wnt signaling. Circ Res. 2009 May 8;104(9):1095-102. doi: 10.1161/CIRCRESAHA.108.192138. Epub 2009 Apr 2. PMID: 19342601; PMCID: PMC2821014.

67: Shen C, Lie P, Miao T, Yu M, Lu Q, Feng T, Li J, Zu T, Liu X, Li H. Conditioned medium from umbilical cord mesenchymal stem cells induces migration and angiogenesis. Mol Med Rep. 2015 Jul;12(1):20-30. doi: 10.3892/mmr.2015.3409. Epub 2015 Mar 4. PMID: 25739039; PMCID: PMC4438972.

68: Zeng Z, Inoue K, Sun H, Leng T, Feng X, Zhu L, Xiong ZG. TRPM7 regulates vascular endothelial cell adhesion and tube formation. Am J Physiol Cell Physiol. 2015 Feb 15;308(4):C308-18. doi: 10.1152/ajpcell.00275.2013. Epub 2014 Dec 3. PMID: 25472964; PMCID: PMC4329423.

69: Rix A, Fokong S, Heringer S, Pjontek R, Kabelitz L, Theek B, Brockmann MA, Wiesmann M, Kiessling F. Molecular Ultrasound Imaging of αvβ3-Integrin Expression in Carotid Arteries of Pigs After Vessel Injury. Invest Radiol. 2016 Dec;51(12):767-775. doi: 10.1097/RLI.0000000000000282. PMID: 27119438.

70: Lin Z, Li R, Liu Y, Zhao Y, Ao N, Wang J, Li L, Wu G. Histatin1-modified thiolated chitosan hydrogels enhance wound healing by accelerating cell adhesion, migration and angiogenesis. Carbohydr Polym. 2020 Feb 15;230:115710. doi: 10.1016/j.carbpol.2019.115710. Epub 2019 Dec 6. PMID: 31887922.

71: Kawase T, Tanaka T, Okuda K, Tsuchimochi M, Oda M, Hara T. Quantitative single-cell motility analysis of platelet-rich plasma-treated endothelial cells in vitro. Cytoskeleton (Hoboken). 2015 May;72(5):246-55. doi: 10.1002/cm.21221. Epub 2015 Apr 28. PMID: 25845465.

72: Yu Y, Liu Q, Guo S, Zhang Q, Tang J, Liu G, Kong D, Li J, Yan S, Wang R, Wang P, Su X, Yu Y. 2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin promotes endothelial cell apoptosis through activation of EP3/p38MAPK/Bcl-2 pathway. J Cell Mol Med. 2017 Dec;21(12):3540-3551. doi: 10.1111/jcmm.13265. Epub 2017 Jul 12. PMID: 28699682; PMCID: PMC5706494.

73: Korybalska K, Kawka E, Breborowicz A, Witowski J. Atorvastatin does not impair endothelial cell wound healing in an in vitro model of vascular injury. J Physiol Pharmacol. 2012 Aug;63(4):389-95. PMID: 23070088.

74: Niu G, Ye T, Qin L, Bourbon PM, Chang C, Zhao S, Li Y, Zhou L, Cui P, Rabinovitz I, Mercurio AM, Zhao D, Zeng H. Orphan nuclear receptor TR3/Nur77 improves wound healing by upregulating the expression of integrin β4. FASEB J. 2015 Jan;29(1):131-40. doi: 10.1096/fj.14-257550. Epub 2014 Oct 17. PMID: 25326539; PMCID: PMC4285545.

75: Zhou S, Zhang P, Liang P, Huang X. The expression of miR-125b regulates angiogenesis during the recovery of heat-denatured HUVECs. Burns. 2015 Jun;41(4):803-11. doi: 10.1016/j.burns.2014.10.012. Epub 2014 Nov 24. PMID: 25468475.

76: Tepeköylü C, Primessnig U, Pölzl L, Graber M, Lobenwein D, Nägele F, Kirchmair E, Pechriggl E, Grimm M, Holfeld J. Shockwaves prevent from heart failure after acute myocardial ischaemia via RNA/protein complexes. J Cell Mol Med. 2017 Apr;21(4):791-801. doi: 10.1111/jcmm.13021. Epub 2016 Dec 20. PMID: 27995765; PMCID: PMC5345685.

77: Phua DC, Humbert PO, Hunziker W. Vimentin regulates scribble activity by protecting it from proteasomal degradation. Mol Biol Cell. 2009 Jun;20(12):2841-55. doi: 10.1091/mbc.e08-02-0199. Epub 2009 Apr 22. PMID: 19386766; PMCID: PMC2695792.

78: Joyce NC, Harris DL, Markov V, Zhang Z, Saitta B. Potential of human umbilical cord blood mesenchymal stem cells to heal damaged corneal endothelium. Mol Vis. 2012;18:547-64. Epub 2012 Mar 2. PMID: 22419848; PMCID: PMC3298421.

79: Li M, Li F, Wang T, Zhao L, Shi Y. Fabrication of carboxymethylcellulose hydrogel containing β-cyclodextrin-eugenol inclusion complexes for promoting diabetic wound healing. J Biomater Appl. 2020 Jan;34(6):851-863. doi: 10.1177/0885328219873254. Epub 2019 Sep 2. PMID: 31475874.

80: Ding Q, Sun P, Zhou H, Wan B, Yin J, Huang Y, Li Q, Yin G, Fan J. Lack of endogenous parathyroid hormone delays fracture healing by inhibiting vascular endothelial growth factor‑mediated angiogenesis. Int J Mol Med. 2018 Jul;42(1):171-181. doi: 10.3892/ijmm.2018.3614. Epub 2018 Apr 3. PMID: 29620150; PMCID: PMC5979887.

81: Tyeb S, Shiekh PA, Verma V, Kumar A. Adipose-Derived Stem Cells (ADSCs) Loaded Gelatin-Sericin-Laminin Cryogels for Tissue Regeneration in Diabetic Wounds. Biomacromolecules. 2020 Feb 10;21(2):294-304. doi: 10.1021/acs.biomac.9b01355. Epub 2019 Dec 11. PMID: 31771325.

82: Bo J, Guan Y, Guo Y, Xie S, Zhang C, Zhang H, Chen Z, Lu J, Meng QH. Impairment of Endothelial Cell Function Induced by Hemoglobin A(1c) and the Potential Mechanisms. Exp Clin Endocrinol Diabetes. 2015 Oct;123(9):529-35. doi: 10.1055/s-0035-1554622. Epub 2015 Jun 11. PMID: 26069073.

83: Zhao Y, Wang Q, Jin Y, Li Y, Nie C, Huang P, Li Z, Zhang B, Su Z, Hong A, Chen X. Discovery and Characterization of a High-Affinity Small Peptide Ligand, H1, Targeting FGFR2IIIc for Skin Wound Healing. Cell Physiol Biochem. 2018;49(3):1033-1048. doi: 10.1159/000493287. Epub 2018 Sep 7. PMID: 30196288.

84: Bartaula-Brevik S, Pedersen TO, Blois AL, Papadakou P, Finne-Wistrand A, Xue Y, Bolstad AI, Mustafa K. Leukocyte transmigration into tissue-engineered constructs is influenced by endothelial cells through Toll-like receptor signaling. Stem Cell Res Ther. 2014 Dec 20;5(6):143. doi: 10.1186/scrt533. PMID: 25528303; PMCID: PMC4445275.

85: Grove BD, Bruchey AK. Intracellular distribution of gravin, a PKA and PKC binding protein, in vascular endothelial cells. J Vasc Res. 2001 Mar- Apr;38(2):163-75. doi: 10.1159/000051043. PMID: 11316952.

86: Chan N, He S, Spee CK, Ishikawa K, Hinton DR. Attenuation of choroidal neovascularization by histone deacetylase inhibitor. PLoS One. 2015 Mar 25;10(3):e0120587. doi: 10.1371/journal.pone.0120587. PMID: 25807249; PMCID: PMC4373846.

87: Huang M, Qiu Q, Zeng S, Xiao Y, Shi M, Zou Y, Ye Y, Liang L, Yang X, Xu H. Niclosamide inhibits the inflammatory and angiogenic activation of human umbilical vein endothelial cells. Inflamm Res. 2015 Dec;64(12):1023-32. doi: 10.1007/s00011-015-0888-8. PMID: 26499405.

88: Wang X, Pan B, Hashimoto Y, Ohkawara H, Xu K, Zeng L, Ikezoe T. Defibrotide Stimulates Angiogenesis and Protects Endothelial Cells from Calcineurin Inhibitor-Induced Apoptosis via Upregulation of AKT/Bcl-xL. Thromb Haemost. 2018 Jan;118(1):161-173. doi: 10.1160/TH17-04-0275. Epub 2018 Jan 5. PMID: 29304536.

89: Oh JY, Choi GE, Lee HJ, Jung YH, Ko SH, Chae CW, Kim JS, Kim SY, Lim JR, Lee CK, Han HJ. High Glucose-Induced Reactive Oxygen Species Stimulates Human Mesenchymal Stem Cell Migration Through Snail and EZH2-Dependent E-Cadherin Repression. Cell Physiol Biochem. 2018;46(5):1749-1767. doi: 10.1159/000489360. Epub 2018 Apr 25. PMID: 29705809.

90: Giordano A, Romano S, Corcione N, Frati G, Zoccai GB, Ferraro P, Messina S, Ottolini S, Romano MF. Tirofiban Positively Regulates β1 Integrin and Favours Endothelial Cell Growth on Polylactic Acid Biopolymer Vascular Scaffold (BVS). J Cardiovasc Transl Res. 2018 Jun;11(3):201-209. doi: 10.1007/s12265-018-9805-1. Epub 2018 Apr 25. PMID: 29696533.

91: Zhong ZF, Hoi PM, Wu GS, Xu ZT, Tan W, Chen XP, Cui L, Wu T, Wang YT. Anti- angiogenic effect of furanodiene on HUVECs in vitro and on zebrafish in vivo. J Ethnopharmacol. 2012 Jun 1;141(2):721-7. doi: 10.1016/j.jep.2011.08.052. Epub 2011 Sep 3. PMID: 21911050.

92: Zhang Y, Niu X, Dong X, Wang Y, Li H. Bioglass enhanced wound healing ability of urine-derived stem cells through promoting paracrine effects between stem cells and recipient cells. J Tissue Eng Regen Med. 2018 Mar;12(3):e1609-e1622. doi: 10.1002/term.2587. Epub 2017 Nov 1. Erratum in: J Tissue Eng Regen Med. 2019 Nov;13(11):2126. PMID: 29024443.

93: Malinda KM, Wysocki AB, Koblinski JE, Kleinman HK, Ponce ML. Angiogenic laminin-derived peptides stimulate wound healing. Int J Biochem Cell Biol. 2008;40(12):2771-80. doi: 10.1016/j.biocel.2008.05.025. Epub 2008 Jun 20. PMID: 18603014; PMCID: PMC2707597.

94: Van Bergen T, Vandewalle E, Van de Veire S, Dewerchin M, Stassen JM, Moons L, Stalmans I. The role of different VEGF isoforms in scar formation after glaucoma filtration surgery. Exp Eye Res. 2011 Nov;93(5):689-99. doi: 10.1016/j.exer.2011.08.016. Epub 2011 Sep 1. PMID: 21907194.

95: El-Ftesi S, Chang EI, Longaker MT, Gurtner GC. Aging and diabetes impair the neovascular potential of adipose-derived stromal cells. Plast Reconstr Surg. 2009 Feb;123(2):475-485. doi: 10.1097/PRS.0b013e3181954d08. PMID: 19182604; PMCID: PMC2878769.

96: Pan Y, Wu Q, Qin L, Cai J, Du B. Gold nanoparticles inhibit VEGF165-induced migration and tube formation of endothelial cells via the Akt pathway. Biomed Res Int. 2014;2014:418624. doi: 10.1155/2014/418624. Epub 2014 Jun 1. PMID: 24987682; PMCID: PMC4058682.

97: Adams GN, Stavrou EX, Fang C, Merkulova A, Alaiti MA, Nakajima K, Morooka T, Merkulov S, Larusch GA, Simon DI, Jain MK, Schmaier AH. Prolylcarboxypeptidase promotes angiogenesis and vascular repair. Blood. 2013 Aug 22;122(8):1522-31. doi: 10.1182/blood-2012-10-460360. Epub 2013 Jun 6. PMID: 23744584; PMCID: PMC3750346.

98: Bodnar RJ, Rodgers ME, Chen WC, Wells A. Pericyte regulation of vascular remodeling through the CXC receptor 3. Arterioscler Thromb Vasc Biol. 2013 Dec;33(12):2818-29. doi: 10.1161/ATVBAHA.113.302012. Epub 2013 Oct 17. PMID: 24135023; PMCID: PMC4591000.

99: Song Y, Yu Z, Song B, Guo S, Lei L, Ma X, Su Y. Usnic acid inhibits hypertrophic scarring in a rabbit ear model by suppressing scar tissue angiogenesis. Biomed Pharmacother. 2018 Dec;108:524-530. doi: 10.1016/j.biopha.2018.06.176. Epub 2018 Sep 20. PMID: 30243085.

100: Preininger B, Duda G, Gerigk H, Bruckner J, Ellinghaus A, Sass FA, Perka C, Schmidt-Bleek K, Dienelt A. CD133: enhancement of bone healing by local transplantation of peripheral blood cells in a biologically delayed rat osteotomy model. PLoS One. 2013;8(2):e52650. doi: 10.1371/journal.pone.0052650. Epub 2013 Feb 14. PMID: 23457441; PMCID: PMC3573035.

101: Liu X, Zheng N, Shi YN, Yuan J, Li L. Thyroid hormone induced angiogenesis through the integrin αvβ3/protein kinase D/histone deacetylase 5 signaling pathway. J Mol Endocrinol. 2014 Apr 28;52(3):245-54. doi: 10.1530/JME-13-0252. PMID: 24532656.

102: Lindsey ML, Iyer RP, Zamilpa R, Yabluchanskiy A, DeLeon-Pennell KY, Hall ME, Kaplan A, Zouein FA, Bratton D, Flynn ER, Cannon PL, Tian Y, Jin YF, Lange RA, Tokmina-Roszyk D, Fields GB, de Castro Brás LE. A Novel Collagen Matricryptin Reduces Left Ventricular Dilation Post-Myocardial Infarction by Promoting Scar Formation and Angiogenesis. J Am Coll Cardiol. 2015 Sep 22;66(12):1364-74. doi: 10.1016/j.jacc.2015.07.035. PMID: 26383724; PMCID: PMC4575409.

103: Navone SE, Pascucci L, Dossena M, Ferri A, Invernici G, Acerbi F, Cristini S, Bedini G, Tosetti V, Ceserani V, Bonomi A, Pessina A, Freddi G, Alessandrino A, Ceccarelli P, Campanella R, Marfia G, Alessandri G, Parati EA. Decellularized silk fibroin scaffold primed with adipose mesenchymal stromal cells improves wound healing in diabetic mice. Stem Cell Res Ther. 2014 Jan 14;5(1):7. doi: 10.1186/scrt396. PMID: 24423450; PMCID: PMC4055150.

104: Cho SG, Yi Z, Pang X, Yi T, Wang Y, Luo J, Wu Z, Li D, Liu M. Kisspeptin-10, a KISS1-derived decapeptide, inhibits tumor angiogenesis by suppressing Sp1-mediated VEGF expression and FAK/Rho GTPase activation. Cancer Res. 2009 Sep 1;69(17):7062-70. doi: 10.1158/0008-5472.CAN-09-0476. Epub 2009 Aug 11. PMID: 19671799; PMCID: PMC3242001.

105: Lee BNR, Chang HK, Son YS, Lee D, Kwon SM, Kim PH, Cho JY. IFN-γ enhances the wound healing effect of late EPCs (LEPCs) via BST2-mediated adhesion to endothelial cells. FEBS Lett. 2018 May;592(10):1705-1715. doi: 10.1002/1873-3468.13078. Epub 2018 May 16. PMID: 29710419.

106: Shimizu T, Nishihira J, Watanabe H, Abe R, Honda A, Ishibashi T, Shimizu H. Macrophage migration inhibitory factor is induced by thrombin and factor Xa in endothelial cells. J Biol Chem. 2004 Apr 2;279(14):13729-37. doi: 10.1074/jbc.M400150200. Epub 2004 Jan 21. PMID: 14736878.

107: Yun SP, Lee SJ, Oh SY, Jung YH, Ryu JM, Suh HN, Kim MO, Oh KB, Han HJ. Reactive oxygen species induce MMP12-dependent degradation of collagen 5 and fibronectin to promote the motility of human umbilical cord-derived mesenchymal stem cells. Br J Pharmacol. 2014 Jul;171(13):3283-97. doi: 10.1111/bph.12681. PMID: 24627968; PMCID: PMC4080981.

108: Xue M, Thompson P, Sambrook PN, March L, Jackson CJ. Activated protein C stimulates expression of angiogenic factors in human skin cells, angiogenesis in the chick embryo and cutaneous wound healing in rodents. Clin Hemorheol Microcirc. 2006;34(1-2):153-61. PMID: 16543631.

109: Rebaï O, Le Petit-Thevenin J, Bruneau N, Lombardo D, Vérine A. In vitro angiogenic effects of pancreatic bile salt-dependent lipase. Arterioscler Thromb Vasc Biol. 2005 Feb;25(2):359-64. doi: 10.1161/01.ATV.0000151618.49109.bd. Epub 2004 Nov 29. PMID: 15569825.

110: Chalenko YM, Sysolyatina EV, Sobyanin KA, Kapkaeva MR, Lavrikova A, Kalinin E, Scheglovitova ON, Ermolaeva SA. Topical treatment with the bacterium-derived c-Met agonist InlB321/15 accelerates healing in the abrasion wound mouse model. Arch Dermatol Res. 2018 Dec;310(10):849-856. doi: 10.1007/s00403-018-1870-4. Epub 2018 Oct 10. PMID: 30306262.

111: Amin HD, Olsen I, Knowles J, Dard M, Donos N. A tyrosine-rich amelogenin peptide promotes neovasculogenesis in vitro and ex vivo. Acta Biomater. 2014 May;10(5):1930-9. doi: 10.1016/j.actbio.2013.11.027. Epub 2013 Dec 7. PMID: 24321350.

112: Lim WB, Kim JS, Ko YJ, Kwon H, Kim SW, Min HK, Kim O, Choi HR, Kim OJ. Effects of 635nm light-emitting diode irradiation on angiogenesis in CoCl(2) -exposed HUVECs. Lasers Surg Med. 2011 Apr;43(4):344-52. doi: 10.1002/lsm.21038. PMID: 21500230.

113: Zhu GS, Tang LY, Lv DL, Jiang M. Total Flavones of Abelmoschus manihot Exhibits Pro-Angiogenic Activity by Activating the VEGF-A/VEGFR2-PI3K/Akt Signaling Axis. Am J Chin Med. 2018;46(3):567-583. doi: 10.1142/S0192415X18500295. Epub 2018 Mar 29. PMID: 29595071.

114: Su L, Zhang Y, He K, Wei S, Pei H, Wang Q, Yang D, Yang Y. Activation of transient receptor potential vanilloid 1 accelerates re-endothelialization and inhibits neointimal formation after vascular injury. J Vasc Surg. 2017 Jan;65(1):197-205.e2. doi: 10.1016/j.jvs.2015.12.037. Epub 2016 Mar 2. PMID: 26947234.

115: Nagano M, Kimura K, Yamashita T, Ohneda K, Nozawa D, Hamada H, Yoshikawa H, Ochiai N, Ohneda O. Hypoxia responsive mesenchymal stem cells derived from human umbilical cord blood are effective for bone repair. Stem Cells Dev. 2010 Aug;19(8):1195-210. doi: 10.1089/scd.2009.0447. PMID: 20345248.

116: Kang HJ, Kumar S, D'Elia A, Dash B, Nanda V, Hsia HC, Yarmush ML, Berthiaume F. Self-assembled elastin-like polypeptide fusion protein coacervates as competitive inhibitors of advanced glycation end-products enhance diabetic wound healing. J Control Release. 2021 May 10;333:176-187. doi: 10.1016/j.jconrel.2021.03.032. Epub 2021 Mar 27. PMID: 33781808.

117: Sieminski AL, Hebbel RP, Gooch KJ. Improved microvascular network in vitro by human blood outgrowth endothelial cells relative to vessel-derived endothelial cells. Tissue Eng. 2005 Sep-Oct;11(9-10):1332-45. doi: 10.1089/ten.2005.11.1332. PMID: 16259589.

118: Garrido-Martín EM, Blanco FJ, Roquè M, Novensà L, Tarocchi M, Lang UE, Suzuki T, Friedman SL, Botella LM, Bernabéu C. Vascular injury triggers Krüppel- like factor 6 mobilization and cooperation with specificity protein 1 to promote endothelial activation through upregulation of the activin receptor-like kinase 1 gene. Circ Res. 2013 Jan 4;112(1):113-27. doi: 10.1161/CIRCRESAHA.112.275586. Epub 2012 Oct 9. PMID: 23048070; PMCID: PMC3537907.

119: Protasiewicz M, Kuliczkowski W, Woznicka AK, Szymkiewicz P, Derkacz A, Andrzej M, Dziegiel P. Influence of low-power laser illumination on pro- inflammatory response in human endothelial cells stimulated with interleukin-1a. In Vivo. 2013 May-Jun;27(3):313-9. PMID: 23606686.

120: Bou Khzam L, Boulahya R, Abou-Saleh H, Hachem A, Zaid Y, Merhi Y. Soluble CD40 ligand stimulates the pro-angiogenic function of peripheral blood angiogenic outgrowth cells via increased release of matrix metalloproteinase-9. PLoS One. 2013 Dec 16;8(12):e84289. doi: 10.1371/journal.pone.0084289. PMID: 24358353; PMCID: PMC3865292.

121: Sepp NT, Cornelius LA, Romani N, Li LJ, Caughman SW, Lawley TJ, Swerlick RA. Polarized expression and basic fibroblast growth factor-induced down- regulation of the alpha 6 beta 4 integrin complex on human microvascular endothelial cells. J Invest Dermatol. 1995 Feb;104(2):266-70. doi: 10.1111/1523-1747.ep12612807. PMID: 7829884.

122: Ledford KJ, Murphy N, Zeigler F, Bartel RL, Tubo R. Therapeutic potential of ixmyelocel-T, an expanded autologous multicellular therapy for treatment of ischemic cardiovascular diseases. Stem Cell Res Ther. 2015 Mar 13;6(1):25. doi: 10.1186/s13287-015-0007-3. PMID: 25889271; PMCID: PMC4413547.

123: Kim JS, Kim JM, Jung HC, Song IS. Helicobacter pylori down-regulates the receptors of vascular endothelial growth factor and angiopoietin in vascular endothelial cells: implications in the impairment of gastric ulcer healing. Dig Dis Sci. 2004 May;49(5):778-86. doi: 10.1023/b:ddas.0000030089.76514.e4. PMID: 15259499.

124: Solovey AN, Gui L, Chang L, Enenstein J, Browne PV, Hebbel RP. Identification and functional assessment of endothelial P1H12. J Lab Clin Med. 2001 Nov;138(5):322-31. doi: 10.1067/mlc.2001.118519. PMID: 11709656.

125: Cui G, Xin Q, Tseng HHL, Hoi MP, Wang Y, Yang B, Choi I, Wang Y, Yuan R, Chen K, Cong W, Lee SM. A novel Ca2+ current blocker promotes angiogenesis and cardiac healing after experimental myocardial infarction in mice. Pharmacol Res. 2018 Aug;134:109-117. doi: 10.1016/j.phrs.2018.06.005. Epub 2018 Jun 8. PMID: 29890255.

126: Bertl K, An N, Bruckmann C, Dard M, Andrukhov O, Matejka M, Rausch-Fan X. Effects of enamel matrix derivative on proliferation/viability, migration, and expression of angiogenic factor and adhesion molecules in endothelial cells in vitro. J Periodontol. 2009 Oct;80(10):1622-30. doi: 10.1902/jop.2009.090157. PMID: 19792852.

127: Profirovic J, Strekalova E, Urao N, Krbanjevic A, Andreeva AV, Varadarajan S, Fukai T, Hen R, Ushio-Fukai M, Voyno-Yasenetskaya TA. A novel regulator of angiogenesis in endothelial cells: 5-hydroxytriptamine 4 receptor. Angiogenesis. 2013 Jan;16(1):15-28. doi: 10.1007/s10456-012-9296-7. Epub 2012 Aug 18. PMID: 22903372; PMCID: PMC3656662.

128: Ryu JM, Han HJ. Autotaxin-LPA axis regulates hMSC migration by adherent junction disruption and cytoskeletal rearrangement via LPAR1/3-dependent PKC/GSK3β/β-catenin and PKC/Rho GTPase pathways. Stem Cells. 2015 Mar;33(3):819-32. doi: 10.1002/stem.1882. PMID: 25376707.

129: Kuo CH, Huang YH, Chen PK, Lee GH, Tang MJ, Conway EM, Shi GY, Wu HL. VEGF- Induced Endothelial Podosomes via ROCK2-Dependent Thrombomodulin Expression Initiate Sprouting Angiogenesis. Arterioscler Thromb Vasc Biol. 2021 May 5;41(5):1657-1671. doi: 10.1161/ATVBAHA.121.315931. Epub 2021 Mar 18. PMID: 33730876.

130: Zhang CZ, Mu XF, Xu XX, Qiu F, Lin JS, Diao Y. [The effect of Connexin43 downregulation on biological functions of HUVEC]. Yao Xue Xue Bao. 2015 Mar;50(3):298-304. Chinese. PMID: 26118108.

131: Sathanoori R, Bryl-Gorecka P, Müller CE, Erb L, Weisman GA, Olde B, Erlinge D. P2Y2 receptor modulates shear stress-induced cell alignment and actin stress fibers in human umbilical vein endothelial cells. Cell Mol Life Sci. 2017 Feb;74(4):731-746. doi: 10.1007/s00018-016-2365-0. Epub 2016 Sep 20. PMID: 27652381; PMCID: PMC5272905.

132: Lee HJ, Jung YH, Choi GE, Ko SH, Lee SJ, Lee SH, Han HJ. BNIP3 induction by hypoxia stimulates FASN-dependent free fatty acid production enhancing therapeutic potential of umbilical cord blood-derived human mesenchymal stem cells. Redox Biol. 2017 Oct;13:426-443. doi: 10.1016/j.redox.2017.07.004. Epub 2017 Jul 4. PMID: 28704726; PMCID: PMC5508529.

133: Uchiyama A, Yamada K, Perera B, Ogino S, Yokoyama Y, Takeuchi Y, Ishikawa O, Motegi SI. Protective effect of MFG-E8 after cutaneous ischemia-reperfusion injury. J Invest Dermatol. 2015 Apr;135(4):1157-1165. doi: 10.1038/jid.2014.515. Epub 2014 Dec 10. PMID: 25493650.

134: Park JY, Kang YW, Choi BY, Yang YC, Cho BP, Cho WG. CCL11 promotes angiogenic activity by activating the PI3K/Akt pathway in HUVECs. J Recept Signal Transduct Res. 2017 Aug;37(4):416-421. doi: 10.1080/10799893.2017.1298132. Epub 2017 Mar 9. PMID: 28279120.

135: Tahir SA, Park S, Thompson TC. Caveolin-1 regulates VEGF-stimulated angiogenic activities in prostate cancer and endothelial cells. Cancer Biol Ther. 2009 Dec;8(23):2286-96. doi: 10.4161/cbt.8.23.10138. Epub 2009 Dec 19. PMID: 19923922; PMCID: PMC2887683.

136: Herrmann M, Stanić B, Hildebrand M, Alini M, Verrier S. In vitro simulation of the early proinflammatory phase in fracture healing reveals strong immunomodulatory effects of CD146-positive mesenchymal stromal cells. J Tissue Eng Regen Med. 2019 Aug;13(8):1466-1481. doi: 10.1002/term.2902. Epub 2019 Jun 25. PMID: 31132812.

137: Montesinos MC, Gadangi P, Longaker M, Sung J, Levine J, Nilsen D, Reibman J, Li M, Jiang CK, Hirschhorn R, Recht PA, Ostad E, Levin RI, Cronstein BN. Wound healing is accelerated by agonists of adenosine A2 (G alpha s-linked) receptors. J Exp Med. 1997 Nov 3;186(9):1615-20. doi: 10.1084/jem.186.9.1615. PMID: 9348321; PMCID: PMC2199104.

138: Hsu CW, Yuan K, Tseng CC. The negative effect of platelet-rich plasma on the growth of human cells is associated with secreted thrombospondin-1. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009 Feb;107(2):185-92. doi: 10.1016/j.tripleo.2008.07.016. Epub 2008 Sep 20. PMID: 18805712.

139: Miyashita K, Itoh H, Sawada N, Fukunaga Y, Sone M, Yamahara K, Yurugi- Kobayashi T, Park K, Nakao K. Adrenomedullin provokes endothelial Akt activation and promotes vascular regeneration both in vitro and in vivo. FEBS Lett. 2003 Jun 5;544(1-3):86-92. doi: 10.1016/s0014-5793(03)00484-8. PMID: 12782295.

140: Ni H, Zhao W, Kong X, Li H, Ouyang J. Celastrol inhibits lipopolysaccharide-induced angiogenesis by suppressing TLR4-triggered nuclear factor-kappa B activation. Acta Haematol. 2014;131(2):102-11. doi: 10.1159/000354770. Epub 2013 Oct 18. PMID: 24157922.

141: Yuan X, Arkonac DE, Chao PH, Vunjak-Novakovic G. Electrical stimulation enhances cell migration and integrative repair in the meniscus. Sci Rep. 2014 Jan 14;4:3674. doi: 10.1038/srep03674. PMID: 24419206; PMCID: PMC3891019.

142: Li S, Song C, Yang S, Yu W, Zhang W, Zhang G, Xi Z, Lu E. Supercritical CO2 foamed composite scaffolds incorporating bioactive lipids promote vascularized bone regeneration via Hif-1α upregulation and enhanced type H vessel formation. Acta Biomater. 2019 Aug;94:253-267. doi: 10.1016/j.actbio.2019.05.066. Epub 2019 May 31. PMID: 31154054.

143: Liu CT, Bi KW, Huang CC, Wu HT, Ho HY, S Pang JH, Huang ST. Davallia bilabiata exhibits anti-angiogenic effect with modified MMP-2/TIMP-2 secretion and inhibited VEGF ligand/receptors expression in vascular endothelial cells. J Ethnopharmacol. 2017 Jan 20;196:213-224. doi: 10.1016/j.jep.2016.12.019. Epub 2016 Dec 16. PMID: 27993633.

144: Cruse JM, Wang H, Lewis RE, Cespedes J, Morrison RS 3rd, Lineaweaver WC, Dilioglou S. Cellular and molecular alterations in spinal cord injury patients with pressure ulcers: a preliminary report. Exp Mol Pathol. 2002 Apr;72(2):124-31. doi: 10.1006/exmp.2002.2420. PMID: 11890721.

145: Jiang H, Weyrich AS, Zimmerman GA, McIntyre TM. Endothelial cell confluence regulates cyclooxygenase-2 and prostaglandin E2 production that modulate motility. J Biol Chem. 2004 Dec 31;279(53):55905-13. doi: 10.1074/jbc.M406094200. Epub 2004 Oct 13. PMID: 15485847.

146: Hughes SK, Wacker BK, Kaneda MM, Elbert DL. Fluid shear stress modulates cell migration induced by sphingosine 1-phosphate and vascular endothelial growth factor. Ann Biomed Eng. 2005 Aug;33(8):1003-14. doi: 10.1007/s10439-005-5756-1. PMID: 16133909.

147: Warboys CM, de Luca A, Amini N, Luong L, Duckles H, Hsiao S, White A, Biswas S, Khamis R, Chong CK, Cheung WM, Sherwin SJ, Bennett MR, Gil J, Mason JC, Haskard DO, Evans PC. Disturbed flow promotes endothelial senescence via a p53-dependent pathway. Arterioscler Thromb Vasc Biol. 2014 May;34(5):985-95. doi: 10.1161/ATVBAHA.114.303415. Epub 2014 Mar 20. PMID: 24651677.

148: Lee SJ, Jung YH, Oh SY, Yun SP, Han HJ. Melatonin enhances the human mesenchymal stem cells motility via melatonin receptor 2 coupling with Gαq in skin wound healing. J Pineal Res. 2014 Nov;57(4):393-407. doi: 10.1111/jpi.12179. Epub 2014 Oct 7. PMID: 25250716.

149: Yu S, Li L, Tian W, Nie D, Mu W, Qiu F, Liu Y, Liu X, Wang X, Du Z, Chu WF, Yang B. PEP06 polypeptide 30 exerts antitumour effect in colorectal carcinoma via inhibiting epithelial-mesenchymal transition. Br J Pharmacol. 2018 Aug;175(15):3111-3130. doi: 10.1111/bph.14352. Epub 2018 Jun 15. PMID: 29722931; PMCID: PMC6031886.

150: Chen PK, Chang BI, Kuo CH, Chen PS, Cho CF, Chang CF, Shi GY, Wu HL. Thrombomodulin functions as a plasminogen receptor to modulate angiogenesis. FASEB J. 2013 Nov;27(11):4520-31. doi: 10.1096/fj.13-227561. Epub 2013 Aug 13. PMID: 23943648.

151: Powerski MJ, Henrich D, Sander A, Wastl D, Ludwig K, Marzi I. CD133+CD34+ stem cells are mobilized after musculoskeletal surgery and target endothelium activated by surgical wound fluid. Langenbecks Arch Surg. 2011 Mar;396(3):379-87. doi: 10.1007/s00423-010-0626-1. Epub 2010 Mar 7. PMID: 20213459.

152: Chen X, Song Z, Chen R, Tan S, Huang C, Liu Y, Cheng B, Fu Q. Lysophosphatidic acid enhanced the osteogenic and angiogenic capability of osteoblasts via LPA1/3 receptor. Connect Tissue Res. 2019 Mar;60(2):85-94. doi: 10.1080/03008207.2018.1439485. Epub 2018 Mar 16. PMID: 29447019.

153: Han JK, Kim HL, Jeon KH, Choi YE, Lee HS, Kwon YW, Jang JJ, Cho HJ, Kang HJ, Oh BH, Park YB, Kim HS. Peroxisome proliferator-activated receptor-δ activates endothelial progenitor cells to induce angio-myogenesis through matrix metallo-proteinase-9-mediated insulin-like growth factor-1 paracrine networks. Eur Heart J. 2013 Jun;34(23):1755-65. doi: 10.1093/eurheartj/ehr365. Epub 2011 Sep 14. PMID: 21920965.

154: Wu W, Okamoto O, Kato A, Matsuo N, Nomizu M, Yoshioka H, Fujiwara S. Dermatopontin regulates fibrin formation and its biological activity. J Invest Dermatol. 2014 Jan;134(1):256-263. doi: 10.1038/jid.2013.305. Epub 2013 Jul 22. PMID: 23877568.

155: Kim JS, Yu HK, Ahn JH, Lee HJ, Hong SW, Jung KH, Chang SI, Hong YK, Joe YA, Byun SM, Lee SK, Chung SI, Yoon Y. Human apolipoprotein(a) kringle V inhibits angiogenesis in vitro and in vivo by interfering with the activation of focal adhesion kinases. Biochem Biophys Res Commun. 2004 Jan 16;313(3):534-40. doi: 10.1016/j.bbrc.2003.11.148. PMID: 14697222.

156: Mimura K, Tomimatsu T, Sharentuya N, Tskitishvili E, Kinugasa-Taniguchi Y, Kanagawa T, Kimura T. Nicotine restores endothelial dysfunction caused by excess sFlt1 and sEng in an in vitro model of preeclamptic vascular endothelium: a possible therapeutic role of nicotinic acetylcholine receptor (nAChR) agonists for preeclampsia. Am J Obstet Gynecol. 2010 May;202(5):464.e1-6. doi: 10.1016/j.ajog.2010.01.037. Epub 2010 Mar 11. PMID: 20223446.

157: Zhu ML, Wang G, Wang H, Guo YM, Song P, Xu J, Li P, Wang S, Yang L. Amorphous nano-selenium quantum dots improve endothelial dysfunction in rats and prevent atherosclerosis in mice through Na+/H+ exchanger 1 inhibition. Vascul Pharmacol. 2019 Apr;115:26-32. doi: 10.1016/j.vph.2019.01.005. Epub 2019 Jan 26. PMID: 30695730.

158: Dance M, Montagner A, Yart A, Masri B, Audigier Y, Perret B, Salles JP, Raynal P. The adaptor protein Gab1 couples the stimulation of vascular endothelial growth factor receptor-2 to the activation of phosphoinositide 3-kinase. J Biol Chem. 2006 Aug 11;281(32):23285-95. doi: 10.1074/jbc.M600987200. Epub 2006 Jun 20. PMID: 16787925.

159: Slupsky JR, Kalbas M, Willuweit A, Henn V, Kroczek RA, Müller-Berghaus G. Activated platelets induce tissue factor expression on human umbilical vein endothelial cells by ligation of CD40. Thromb Haemost. 1998 Dec;80(6):1008-14. PMID: 9869175.

160: Goertz O, Lauer H, von der Lohe L, Lehnhardt M, Schossleitner K, Petzelbauer M, Petzelbauer P. Peptide XIB13 reduces capillary leak in a rodent burn model. Microvasc Res. 2014 May;93:98-104. doi: 10.1016/j.mvr.2014.04.003. Epub 2014 Apr 24. Erratum in: Microvasc Res. 2015 May;99:127. Dosage error in article text. PMID: 24769395.

161: Fan Z, Liao X, Tian Y, Xuzhuzi X, Nie Y. A prevascularized nerve conduit based on a stem cell sheet effectively promotes the repair of transected spinal cord injury. Acta Biomater. 2020 Jan 1;101:304-313. doi: 10.1016/j.actbio.2019.10.042. Epub 2019 Oct 31. PMID: 31678739.

162: Kim YM, Youn SW, Sudhahar V, Das A, Chandhri R, Cuervo Grajal H, Kweon J, Leanhart S, He L, Toth PT, Kitajewski J, Rehman J, Yoon Y, Cho J, Fukai T, Ushio-Fukai M. Redox Regulation of Mitochondrial Fission Protein Drp1 by Protein Disulfide Isomerase Limits Endothelial Senescence. Cell Rep. 2018 Jun 19;23(12):3565-3578. doi: 10.1016/j.celrep.2018.05.054. PMID: 29924999; PMCID: PMC6324937.

163: Yang H, Li X, Ma J, Lv X, Zhao S, Lang W, Zhang Y. Blockade of the intermediate-conductance Ca(2+)-activated K+ channel inhibits the angiogenesis induced by epidermal growth factor in the treatment of corneal alkali burn. Exp Eye Res. 2013 May;110:76-87. doi: 10.1016/j.exer.2013.02.015. Epub 2013 Mar 7. PMID: 23482085.

164: Ackermann M, Pabst AM, Houdek JP, Ziebart T, Konerding MA. Priming with proangiogenic growth factors and endothelial progenitor cells improves revascularization in linear diabetic wounds. Int J Mol Med. 2014 Apr;33(4):833-9. doi: 10.3892/ijmm.2014.1630. Epub 2014 Jan 21. PMID: 24452195; PMCID: PMC3976131.

165: Vidinský B, Gál P, Pilátová M, Vidová Z, Solár P, Varinská L, Ivanová L, Mojžíš J. Anti-proliferative and anti-angiogenic effects of CB2R agonist (JWH-133) in non-small lung cancer cells (A549) and human umbilical vein endothelial cells: an in vitro investigation. Folia Biol (Praha). 2012;58(2):75-80. PMID: 22578958.

166: Liu ZJ, Daftarian P, Kovalski L, Wang B, Tian R, Castilla DM, Dikici E, Perez VL, Deo S, Daunert S, Velazquez OC. Directing and Potentiating Stem Cell- Mediated Angiogenesis and Tissue Repair by Cell Surface E-Selectin Coating. PLoS One. 2016 Apr 22;11(4):e0154053. doi: 10.1371/journal.pone.0154053. PMID: 27104647; PMCID: PMC4841581.

167: Tang N, Shi L, Yu Z, Dong P, Wang C, Huo X, Zhang B, Huang S, Deng S, Liu K, Ma T, Wang X, Wu L, Ma XC. Gamabufotalin, a major derivative of bufadienolide, inhibits VEGF-induced angiogenesis by suppressing VEGFR-2 signaling pathway. Oncotarget. 2016 Jan 19;7(3):3533-47. doi: 10.18632/oncotarget.6514. PMID: 26657289; PMCID: PMC4823125.

168: Shi X, Liu M, Li D, Wang J, Aneja R, Zhou J. Cep70 contributes to angiogenesis by modulating microtubule rearrangement and stimulating cell polarization and migration. Cell Cycle. 2012 Apr 15;11(8):1554-63. doi: 10.4161/cc.19954. Epub 2012 Apr 15. PMID: 22437770.

169: Liu X, Zhao D, James L, Li J, Zeng H. Requirement of the nuclear localization of transcription enhancer factor 3 for proliferation, migration, tube formation, and angiogenesis induced by vascular endothelial growth factor. FASEB J. 2011 Apr;25(4):1188-97. doi: 10.1096/fj.10-167619. Epub 2010 Dec 17. PMID: 21169383.

170: Kwon H, Kwon JY, Song J, Maeng YS. Decreased Lymphangiogenic Activities and Genes Expression of Cord Blood Lymphatic Endothelial Progenitor Cells (VEGFR3+/Pod+/CD11b+ Cells) in Patient with Preeclampsia. Int J Mol Sci. 2021 Apr 19;22(8):4237. doi: 10.3390/ijms22084237. PMID: 33921847; PMCID: PMC8073258.

171: Lee H, Goetzl EJ, An S. Lysophosphatidic acid and sphingosine 1-phosphate stimulate endothelial cell wound healing. Am J Physiol Cell Physiol. 2000 Mar;278(3):C612-8. doi: 10.1152/ajpcell.2000.278.3.C612. PMID: 10712250.

172: Kleinschmidt K, Ploeger F, Nickel J, Glockenmeier J, Kunz P, Richter W. Enhanced reconstruction of long bone architecture by a growth factor mutant combining positive features of GDF-5 and BMP-2. Biomaterials. 2013 Aug;34(24):5926-36. doi: 10.1016/j.biomaterials.2013.04.029. Epub 2013 May 13. PMID: 23680368.

173: Sundlisaeter E, Edelmann RJ, Hol J, Sponheim J, Küchler AM, Weiss M, Udalova IA, Midwood KS, Kasprzycka M, Haraldsen G. The alarmin IL-33 is a notch target in quiescent endothelial cells. Am J Pathol. 2012 Sep;181(3):1099-111. doi: 10.1016/j.ajpath.2012.06.003. Epub 2012 Jul 16. PMID: 22809957.

174: Zlot C, Ingle G, Hongo J, Yang S, Sheng Z, Schwall R, Paoni N, Wang F, Peale FV Jr, Gerritsen ME. Stanniocalcin 1 is an autocrine modulator of endothelial angiogenic responses to hepatocyte growth factor. J Biol Chem. 2003 Nov 28;278(48):47654-9. doi: 10.1074/jbc.M301353200. Epub 2003 Sep 17. PMID: 14500721.

175: Longmate WM, Lyons SP, Chittur SV, Pumiglia KM, Van De Water L, DiPersio CM. Suppression of integrin α3β1 by α9β1 in the epidermis controls the paracrine resolution of wound angiogenesis. J Cell Biol. 2017 May 1;216(5):1473-1488. doi: 10.1083/jcb.201510042. Epub 2017 Apr 17. PMID: 28416479; PMCID: PMC5412555.

176: Wang MJ, Du DY, Fan W, Zhang C, Liu Y, Fan JH, Yuan ST, Lin SS. [Effects and mechanisms of Xiao-Ai-Ping injection on angiogenesis]. Yao Xue Xue Bao. 2016 Feb;51(2):309-15. Chinese. PMID: 29856586.

177: van Gils JM, Stutterheim J, van Duijn TJ, Zwaginga JJ, Porcelijn L, de Haas M, Hordijk PL. HPA-1a alloantibodies reduce endothelial cell spreading and monolayer integrity. Mol Immunol. 2009 Jan;46(3):406-15. doi: 10.1016/j.molimm.2008.10.015. Epub 2008 Nov 26. PMID: 19038456.

178: Gallardo-Vara E, Tual-Chalot S, Botella LM, Arthur HM, Bernabeu C. Soluble endoglin regulates expression of angiogenesis-related proteins and induction of arteriovenous malformations in a mouse model of hereditary hemorrhagic telangiectasia. Dis Model Mech. 2018 Sep 21;11(9):dmm034397. doi: 10.1242/dmm.034397. PMID: 30108051; PMCID: PMC6176985.

179: Bruns AF, Yuldasheva N, Latham AM, Bao L, Pellet-Many C, Frankel P, Stephen SL, Howell GJ, Wheatcroft SB, Kearney MT, Zachary IC, Ponnambalam S. A heat- shock protein axis regulates VEGFR2 proteolysis, blood vessel development and repair. PLoS One. 2012;7(11):e48539. doi: 10.1371/journal.pone.0048539. Epub 2012 Nov 6. PMID: 23139789; PMCID: PMC3491040.

180: Zhang H, Issekutz AC. Down-modulation of monocyte transendothelial migration and endothelial adhesion molecule expression by fibroblast growth factor: reversal by the anti-angiogenic agent SU6668. Am J Pathol. 2002 Jun;160(6):2219-30. doi: 10.1016/S0002-9440(10)61169-8. PMID: 12057924; PMCID: PMC1850845.

181: Visuri MT, Honkonen KM, Hartiala P, Tervala TV, Halonen PJ, Junkkari H, Knuutinen N, Ylä-Herttuala S, Alitalo KK, Saarikko AM. VEGF-C and VEGF-C156S in the pro-lymphangiogenic growth factor therapy of lymphedema: a large animal study. Angiogenesis. 2015 Jul;18(3):313-26. doi: 10.1007/s10456-015-9469-2. Epub 2015 May 28. PMID: 26018927.

182: Gallardo-Vara E, Blanco FJ, Roqué M, Friedman SL, Suzuki T, Botella LM, Bernabeu C. Transcription factor KLF6 upregulates expression of metalloprotease MMP14 and subsequent release of soluble endoglin during vascular injury. Angiogenesis. 2016 Apr;19(2):155-71. doi: 10.1007/s10456-016-9495-8. Epub 2016 Feb 5. PMID: 26850053; PMCID: PMC4819519.

183: Tuxen AJ, Orchard D. Solitary mastocytoma occurring at a site of trauma. Australas J Dermatol. 2009 May;50(2):133-5. doi: 10.1111/j.1440-0960.2009.00526.x. PMID: 19397569.

184: Nagaraj SR, Shilpa P, Rachaiah K, Salimath BP. Crosstalk between VEGF and MTA1 signaling pathways contribute to aggressiveness of breast carcinoma. Mol Carcinog. 2015 May;54(5):333-50. doi: 10.1002/mc.22104. Epub 2013 Nov 22. PMID: 24265228.

185: Grelier A, Cras A, Balitrand N, Delmau C, Lecourt S, Lepelletier Y, Riesterer H, Freida D, Lataillade JJ, Lebousse-Kerdiles MC, Cuccini W, Peffault de Latour R, Marolleau JP, Uzan G, Larghero J, Vanneaux V. Toll-like receptor 3 regulates cord blood-derived endothelial cell function in vitro and in vivo. Angiogenesis. 2013 Oct;16(4):821-36. doi: 10.1007/s10456-013-9358-5. Epub 2013 Jun 8. PMID: 23748743.

186: Al-Otaiby M, Tassi E, Schmidt MO, Chien CD, Baker T, Salas AG, Xu J, Furlong M, Schlegel R, Riegel AT, Wellstein A. Role of the nuclear receptor coactivator AIB1/SRC-3 in angiogenesis and wound healing. Am J Pathol. 2012 Apr;180(4):1474-84. doi: 10.1016/j.ajpath.2011.12.032. Epub 2012 Feb 14. PMID: 22342158; PMCID: PMC3349901.

187: Lee HK, Chauhan SK, Kay E, Dana R. Flt-1 regulates vascular endothelial cell migration via a protein tyrosine kinase-7-dependent pathway. Blood. 2011 May 26;117(21):5762-71. doi: 10.1182/blood-2010-09-306928. Epub 2011 Apr 1. PMID: 21460247; PMCID: PMC3110033.

188: Ohnuki H, Inoue H, Takemori N, Nakayama H, Sakaue T, Fukuda S, Miwa D, Nishiwaki E, Hatano M, Tokuhisa T, Endo Y, Nose M, Higashiyama S. BAZF, a novel component of cullin3-based E3 ligase complex, mediates VEGFR and Notch cross- signaling in angiogenesis. Blood. 2012 Mar 15;119(11):2688-98. doi: 10.1182/blood-2011-03-345306. Epub 2012 Jan 25. PMID: 22279058.

189: Dasgupta A, Sawant MA, Lavhale MS, Krishnapati LS, Ghaskadbi S, Sitasawad SL. AECHL-1, a novel triterpenoid, targets tumor neo-vasculature and impairs the endothelial cell cytoskeleton. Angiogenesis. 2015 Jul;18(3):283-99. doi: 10.1007/s10456-015-9466-5. Epub 2015 May 8. PMID: 25952529; PMCID: PMC4472952.

190: Hao Y, Qiu QY, Wu J. [Effect of Astragalus polysaccharides in promoting neutrophil-vascular endothelial cell adhesion and expression of related adhesive molecules]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2004 May;24(5):427-30. Chinese. PMID: 15199628.

191: Athanasopoulos AN, Economopoulou M, Orlova VV, Sobke A, Schneider D, Weber H, Augustin HG, Eming SA, Schubert U, Linn T, Nawroth PP, Hussain M, Hammes HP, Herrmann M, Preissner KT, Chavakis T. The extracellular adherence protein (Eap) of Staphylococcus aureus inhibits wound healing by interfering with host defense and repair mechanisms. Blood. 2006 Apr 1;107(7):2720-7. doi: 10.1182/blood-2005-08-3140. Epub 2005 Nov 29. PMID: 16317095; PMCID: PMC1895382.

192: Freeman KW, Bowman BR, Zetter BR. Regenerative protein thymosin beta-4 is a novel regulator of purinergic signaling. FASEB J. 2011 Mar;25(3):907-15. doi: 10.1096/fj.10-169417. Epub 2010 Nov 24. PMID: 21106936.

193: Martinelli R, Kamei M, Sage PT, Massol R, Varghese L, Sciuto T, Toporsian M, Dvorak AM, Kirchhausen T, Springer TA, Carman CV. Release of cellular tension signals self-restorative ventral lamellipodia to heal barrier micro-wounds. J Cell Biol. 2013 Apr 29;201(3):449-65. doi: 10.1083/jcb.201209077. PMID: 23629967; PMCID: PMC3639391.

194: Stalin J, Harhouri K, Hubert L, Subrini C, Lafitte D, Lissitzky JC, Elganfoud N, Robert S, Foucault-Bertaud A, Kaspi E, Sabatier F, Aurrand-Lions M, Bardin N, Holmgren L, Dignat-George F, Blot-Chabaud M. Soluble melanoma cell adhesion molecule (sMCAM/sCD146) promotes angiogenic effects on endothelial progenitor cells through angiomotin. J Biol Chem. 2013 Mar 29;288(13):8991-9000. doi: 10.1074/jbc.M112.446518. Epub 2013 Feb 6. PMID: 23389031; PMCID: PMC3610971.

195: Hytönen J, Leppänen O, Braesen JH, Schunck WH, Mueller D, Jung F, Mrowietz C, Jastroch M, von Bergwelt-Baildon M, Kappert K, Heuser A, Drenckhahn JD, Pieske B, Thierfelder L, Ylä-Herttuala S, Blaschke F. Activation of Peroxisome Proliferator-Activated Receptor-δ as Novel Therapeutic Strategy to Prevent In- Stent Restenosis and Stent Thrombosis. Arterioscler Thromb Vasc Biol. 2016 Aug;36(8):1534-48. doi: 10.1161/ATVBAHA.115.306962. Epub 2016 Jun 9. PMID: 27283742.

196: Weber KS, Nelson PJ, Gröne HJ, Weber C. Expression of CCR2 by endothelial cells : implications for MCP-1 mediated wound injury repair and In vivo inflammatory activation of endothelium. Arterioscler Thromb Vasc Biol. 1999 Sep;19(9):2085-93. doi: 10.1161/01.atv.19.9.2085. PMID: 10479649.

197: Williams PA, Stilhano RS, To VP, Tran L, Wong K, Silva EA. Hypoxia augments outgrowth endothelial cell (OEC) sprouting and directed migration in response to sphingosine-1-phosphate (S1P). PLoS One. 2015 Apr 15;10(4):e0123437. doi: 10.1371/journal.pone.0123437. PMID: 25875493; PMCID: PMC4398361.

198: Malinda KM, Nomizu M, Chung M, Delgado M, Kuratomi Y, Yamada Y, Kleinman HK, Ponce ML. Identification of laminin alpha1 and beta1 chain peptides active for endothelial cell adhesion, tube formation, and aortic sprouting. FASEB J. 1999 Jan;13(1):53-62. PMID: 9872929.

199: Fujita K, Miyamoto T, Saika S. Sonic hedgehog: its expression in a healing cornea and its role in neovascularization. Mol Vis. 2009 May 18;15:1036-44. PMID: 19471603; PMCID: PMC2684749.

200: Jung YH, Lee SJ, Oh SY, Lee HJ, Ryu JM, Han HJ. Oleic acid enhances the motility of umbilical cord blood derived mesenchymal stem cells through EphB2-dependent F-actin formation. Biochim Biophys Acta. 2015 Aug;1853(8):1905-17. doi: 10.1016/j.bbamcr.2015.05.006. Epub 2015 May 9. PMID: 25962624.