Our tissue suppliers are the premiere enterprises for the processing of placental and umbilical membrane proteins.
More than 300,000 patients have been treated and groundbreaking scientific and clinical achievements have been documented in more than 300 peer-reviewed publications.
CRYOTEK process is a proprietary tissue-processing method that preserves the innate biological and structural integrity of the natural placental tissue and therefore preserves and delivers the anti-inflammatory, anti-scarring, and anti-angiogenesis properties of that matrix. In particular, the CRYOTEK process is the ONLY method proven to effectively retain the Heavy Chain Hyaluronic Acid/Pentraxin3 (HC-HA/PTX3) complex, which has been demonstrated to orchestrate an environment that promotes regenerative healing. CRYOTEK-processed tissues are also the only available placental allografts that have been shown to be equivalent to fresh placental tissue and superior to other available placental allografts that are provided in a dehydrated state.
The clinical benefits of the CRYOTEK process have been demonstrated in more than 300 peer-reviewed publications*. By devitalizing the resident living cells, CRYOTEK minimizes the risk of an immune reaction while preserving key components of the extracellular matrix:
- Collagen (types I, III, IV, V and VI)
- Hyaluronic Acid
- Growth Factors
- HC-HA/PTX3 (immuno-signaling complex)
Cryopreserved umbilical cord and amniotic membrane have been demonstrated to promote critical healing actions:
- Modulate inflammation to orchestrate a regenerative healing environment
- Decrease scarring
- Reduce pain associated with inflammation
The SteriTek™ preservation process utilizes a unique technology to yield a shelf-stable product while maintaining the natural hydration of the tissue. The tissue is cleaned, processed and packaged consistent with the CRYOTEK cryopreservation process to maintain the structural and biological integrity of the natural tissue, but is then terminally sterilized using gamma irradiation, yielding a fully hydrated product that can be stored at controlled room temperature.
The Star, Christchurch NZ Issue 8668 7 July 1906 Somasundaram K et al. J Pathol (1970) 100:81-86. Rowlatt U. Virchows Arch. (1979) 381: 353-361.
Placental-based products are currently designated by the U.S. Food and Drug Administration (FDA) as human cell, tissue, and cellular and tissue-based products (HCT/Ps). Our suppliers’ are compliant with all of the regulations of these products including the May 31, 2021 update.